by James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine, Richard Losick
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Product Description
The long-awaited new edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's paper on the structure of the DNA double-helix. Twenty-one concise chapters, co-authored by five highly respected molecular biologists, provide current, authoritative coverage of a fast-changing discipline, giving both historical and basic chemical context. Divided into four parts: Genetics and Chemistry, Central Dogma, Regulation, and Methods. For college instructors, students, and anyone interested in molecular biology and genetics.
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Average Customer Review:
4 of 5 people found the following review helpful:
 "A Scientific Explanation of What Life Is", 2007-11-18
"Molecular Biology of the Gene," James Watson et. al, 5th Edition, CSHL Press, NY 2004, ISBN 0-8053-4635-X, HC 732 pages, includes Preface, Index & inter-active CD-ROM & Website. 11 1/4" x 8 3/4".
J.D. Watson authored first three editions (1965-'76), co-authored 4th ('87) & this 5th ('04) with Baker, Bell, Gann, Levine & Losick. CD works in Windows, but Mac OS X needs Classic for some sections (CHIME). This treatise has 21 chapters divided into 5 major parts: I-Chem.& Genetics, II-Genome Maintenance, III-Genome Expression, IV-Regulation and V-Methodologies.
The discourse best assumes readers to have both core & some advanced study in biology, chemistry, physics & genetics. It is a tutorial & reference manual with detailed covering of history of genetics, Mendelian heredity, elucidation & clarificaion of double helix, Crick's central dogma 1956, genetic code, weak & high-energy bonds, protein structure, conformation, modularity & domains, allostery, topologies, RNA structure, chromosomal sequence & diversity, duplication, chromatin structure & regulation, nucleosome assembly, DNA polymerase, binding & unwinding, replication error & repairs, DNA damage, recombination, transposition, transciption, splicings, shuffling, ribosomes, gene regulation in pro- & eu-karyotes, embryogenesis of Drosophila, genome evolution & methodologies for phage, bacteria, yeast, fly & mouse.
A formidable and now classic text fittingly entrusted to an elite working group in the US, UK and Canada. Most comforting is the liberal use of diagrams on essentially every page & the interactive CD.
9 of 9 people found the following review helpful:
Am Studying for the Biochemistry GRE - This book is golden, 2006-09-18
I got this book to assist for my prep for the Biochemistry GRE - I know a lot about Biology. So this is a great Book - First, It is very readable - I was surprised I was not able to put it down and knocked off 100 pages in record time. Besided that - it is enjoyable and not dull and boring - Second, The great experiments are given and insight into the science reasoning behind them also. This book makes the discover of genetics, DNA, RNA and protein building come alive. Third, this book is very current with research and cites the papers and journals where the important biology, Genetic, molecular & cell biology was published. That alone would save you the time to research and site these for your own research. Lastly, the pictures and recollections of the experimenters and "who knew who" are a total hoot.
9 of 10 people found the following review helpful:
Great Book, 2006-03-17
This book is an awesome teaching guide but the real prize goes to the CD and animations. Where a subject might be a bit hazy in the text, the flash animations on the CD are clear and concise.
5 of 12 people found the following review helpful:
Good book, 2005-11-04
Some books are just very well written-this is one of them!
I like that they leave space in the margin to write notes. Organized more like a book you can read in chapters compared to the Lewin Genes text. Concise and up to date.
Good disc included with lots of great animations.
6 of 86 people found the following review helpful:
 Don't buy this book, 2005-09-23
Buy this book if you are really unintelligent and knows virtually nothing about biology. Really. if you are the person who wants to learn, find an alternative book.
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